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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP2 All Species: 15.15
Human Site: T185 Identified Species: 25.64
UniProt: P46087 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46087 NP_001028886.1 812 89302 T185 I Q W S E E E T E D E E E E K
Chimpanzee Pan troglodytes XP_001162276 812 89269 T185 I Q W S E E E T E D E E E E K
Rhesus Macaque Macaca mulatta XP_001105884 811 89266 T186 V Q W S E E E T E D E E E E V
Dog Lupus familis XP_854432 985 108067 T357 G Q W S E E E T E E E E E K G
Cat Felis silvestris
Mouse Mus musculus Q922K7 793 86733 D170 L W N E E D T D E D E D D D G
Rat Rattus norvegicus XP_235295 772 84951 G187 R K D D K A E G D L Q I N V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416502 682 76182 E159 D Y G A L S S E E E E L L P I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922354 739 83513 D177 M K P E S D D D D D E E E E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610786 891 99823 D229 E D E D D D D D D D D D D D D
Honey Bee Apis mellifera XP_001121968 582 67009 K59 L L K K Q N I K E K L K E L Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787141 1076 119756 S468 M L P I E K A S K K L D K K I
Poplar Tree Populus trichocarpa XP_002300386 476 53332
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194390 671 75524 I148 L E R K S R A I D R K R K K E
Baker's Yeast Sacchar. cerevisiae P40991 618 69794 D94 S L F D D E E D D D E A G L V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.1 68.8 N.A. 75.8 75.1 N.A. N.A. 55.5 N.A. 53 N.A. 41 37.5 N.A. 37.4
Protein Similarity: 100 99.3 96.1 73.8 N.A. 83.2 82 N.A. N.A. 65.3 N.A. 66.5 N.A. 57.6 49.2 N.A. 49.7
P-Site Identity: 100 100 86.6 73.3 N.A. 26.6 6.6 N.A. N.A. 13.3 N.A. 33.3 N.A. 6.6 13.3 N.A. 6.6
P-Site Similarity: 100 100 93.3 86.6 N.A. 60 40 N.A. N.A. 26.6 N.A. 73.3 N.A. 60 40 N.A. 53.3
Percent
Protein Identity: 37.9 N.A. N.A. 39.7 37.4 N.A.
Protein Similarity: 47.6 N.A. N.A. 55.6 52 N.A.
P-Site Identity: 0 N.A. N.A. 0 26.6 N.A.
P-Site Similarity: 0 N.A. N.A. 46.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 15 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 8 22 15 22 15 29 36 50 8 22 15 15 8 % D
% Glu: 8 8 8 15 43 36 43 8 50 15 58 36 43 29 22 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 0 0 0 0 8 0 0 0 0 8 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 0 0 8 0 0 8 8 0 0 0 8 0 0 15 % I
% Lys: 0 15 8 15 8 8 0 8 8 15 8 8 15 22 15 % K
% Leu: 22 22 0 0 8 0 0 0 0 8 15 8 8 15 0 % L
% Met: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 15 0 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 29 0 0 8 0 0 0 0 0 8 0 0 0 8 % Q
% Arg: 8 0 8 0 0 8 0 0 0 8 0 8 0 0 0 % R
% Ser: 8 0 0 29 15 8 8 8 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 8 29 0 0 0 0 0 0 0 % T
% Val: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 15 % V
% Trp: 0 8 29 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _